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1:1 Ratio Cannabis Products – Why and How They Are Helpful

By Danyal Swan September 25, 2021

If you are in search of a marijuana product that helps with alleviating symptoms of anxiety, fibromyalgia, multiple sclerosis, chronic pain, nausea, or insomnia, then using a 1:1 ratio cannabis product may benefit you.

THC and CBD, cannabinoids found within the cannabis plant, have shown a host of therapeutic benefits and, when paired together, may work in tandem to further address symptoms. But first, what is a 1:1 ratio?

Understanding 1:1 Cannabis Ratios

A 1:1 cannabis ratio refers to the amount of THC related to the amount of CBD in a product. THC is the substance found in cannabis that causes a sedative effect. CBD is the substance that does the opposite of THC, causing alertness. Each one can be used alone or in a number of different ratios depending on the effect you desire. However, in equal parts, THC and CBD are considered the perfect pair when it comes to treating medical conditions versus getting high. CBD counteracts the psychoactive effects of THC and can reduce the potential side effects like paranoia and heightened anxiety.

THC And CBD Ratios

With so many different ratios of THC to CBD, it’s no wonder some patients new to cannabis have a hard time deciding where to start. Even people who have experimented with some different variations may be left asking if they have chosen the correct product. It’s very important to note that everyone is different in the way they react to cannabis, and the ratio that is right for one person may not be best for your specific needs. Before we dive into the ratio specifics, it’s important to note how cannabinoids interact with the endocannabinoid system.

The Endocannabinoid System (ECS)

THC and CBD have a range of beneficial impacts on the human body.

Cannabinoids are compounds found in cannabis. They interact with a complex cell-signaling system that is referred to as the endocannabinoid system. This system is responsible for controlling certain regulatory functions in the body, including:

      • Sleep
      • Appetite
      • Memory
      • Mood
      • Reproduction and Fertility

Even when you are not using cannabis, the endocannabinoid system is present and working. The three main components that make up the ECS are endocannabinoids, receptors, and enzymes. All three work together to achieve homeostasis in the body. While there are hundreds of cannabinoids, THC and CBD are the most well-studied in their interactions with the ECS.

How THC Interacts with the ECS

As you likely know, THC is the primary compound associated with cannabis. THC is able to bind to the receptors in the endocannabinoid system to produce a wide range of effects on the body, including the euphoric effects associated with THC. Endocannabinoid receptor 1 (CB1) and endocannabinoid receptor 2 (CB2) are found throughout the central and peripheral nervous systems, respectively. When THC interacts with these receptors, beneficial effects may be had, including pain reduction and appetite stimulation.

How CBD Interacts with the ECS

CBD also interacts with CB1 and CB2 receptors but, instead of binding as THC does, CBD interacts. Instead, CBD interacts with the receptors, preventing endocannabinoids from being broken down, which allows for efficient utilization by the body. In addition, CBD disrupts THC’s binding, which may be the reason CBD can counteract negative effects of THC.

Can You Have Too Little Endocannabinoids?

Some experts, including leading cannabis researcher Dr. Ethan Russo, would tell you yes! The theory consists of the belief that if someone has low levels of endocannabinoids or acceptable levels that do not function properly, illnesses such as migraine headaches, fibromyalgia, and IBS can develop. These conditions can be debilitating, frustrating, and chronic. More research is needed, but these particular conditions often have no other cause and often occur together. Potentially, the endocannabinoid system could be targeted as a form of treatment.


The benefits of CBD and THC in 1:1 ratios, as described by Dr. Barbara Aggarwal, CannaMD:

“CBD and THC each have a wide range of medicinal properties, some synergistic and some unique to each. CBD is non-psychoactive, while THC causes euphoria, which isn’t always desirable, and for some people, it can increase anxiety and even cause paranoia. Since CBD partially blocks THC from binding to CB1 receptors, having a 1:1 ratio reduces the euphoric and other potentially negative sensations while allowing its many benefits. A 1:1 ratio works well for a wide variety of medical conditions, including pain, insomnia, neurologic disorders, and chemotherapy side effects. Additionally, a 1:1 ratio is an excellent starting point for patients new to marijuana to feel relief while learning their individual sensitivity to THC. From this, they can then adjust the ratio if needed for different times of the day or desired effects.”

What Is a 1:1 Edible?

What Is A 1:1 Edible
Wana Soft Chews are one of three 1:1 options, with the other two being Encaps™ and Lozenges.

If you want to know if your edible is a 1:1 infused ration, look at the label. Packaging will display how much THC and how much CBD is in the product. A 1:1 ratio infused edible will read equal amounts (in mg), CBD, and THC.

It’s important to note that, even in a 1:1 ratio, there may be psychoactive effects. When eaten, delta-9-THC converts to delta-11-hydroxy THC, a compound 5x’s more psychoactive than the former. While the CBD may counteract some of the euphoria, edibles are not typically recommended for first-time patients for this reason. In addition, the onset of effects may take up to 90 minutes.

Edibles work differently than EnCaps™ Cannabis Capsules. Patented EnCaps technology encapsulates inherently fat-soluble THC and CBD, rendering them water-soluble instead. This process allows EnCaps Capsules to provide onset of effects in just 30 minutes, without conversion to higher potency cannabinoids.

The 1:1 edibles at MÜV Florida include EnCaps (10mg THC:10mg CBD), Lozenges (5mg THC:5mg CBD) and Wana Soft Chews (10mg THC:10mg CBD). They are all made with the finest quality ingredients and will provide you with a consistent (and delicious) medicating experience.

What is a 1:1 Tincture?

1:1 Tincture
Tinctures are an ideal starting place for newcomers to cannabis regimens, as they allow customizable dosing.

True tinctures are made by combining cannabis in an alcohol-based or glycerin-based concentrate. Cannabis tinctures are commonly used as an alternative to smoking. You can take them sublingually to be absorbed quickly into the body through the thin membranes under your tongue. The 1:1 ratio infused sublingual tincture provides both a relaxing feeling combined with pain relief. MÜV Tincture has the added benefit of encapsulation, allowing the traditionally fat-soluble cannabinoids THC and CBD to mix thoroughly into water.

Tinctures can also be added to many types of drinks and/or meals, for example:

      • Juices
      • Soups
      • Ice Cream or Sherbet
      • Jell-O
      • Smoothies

How Do You Use a 1:1 Tincture?

Finding the right tincture and the correct dose is key to using all cannabis-based therapies, including a 1:1 tincture. We recommend starting with a 5mg dose and tracking the effects in Strainprint™, the mobile cannabis journaling app that determines the efficacy of products for your symptom management. Optimal doses can be determined by tracking each dose, examining the effects, and titrating your dose up as needed. Remember, the dosage is individualized and is different for everyone. For some, tinctures are optimal, but others find 1:1 transdermal patches better, especially for long-lasting relief with minimal upkeep, as these patches may be worn for 72 consecutive hours.

What is a 1:1 Strain?

A 1:1 strain is carefully and specifically bred to create the perfect balance of THC and CBD. 1:1 strains are coveted because they rarely cause anxiety, paranoia, or major feelings of sedation. If you are one of the millions of people who regularly suffer from pain, panic attacks, or fibromyalgia, then a 1:1 strain is likely what you need to start feeling better. The magic of a 1:1 strain lies within the balance that is produced by two completely different components of cannabis that interact harmoniously together to provide therapeutic effects for many common ailments.

Canna-tsu is one such example of a balanced 1:1 strain. The Püre strain is highly-tracked in Strainprint, boasting patient-reported efficacies of 56% for stress and depression, and 69% for upper back pain.

Why 1:1 THC:CBD Ratios Work So Well

THC and CBD go together like peanut butter and jelly. The way they interact in the body is why they work so well together. With what you learned about the different qualities of each, it may seem like THC and CBD would counteract each other, but they actually feed off each other, providing you with a balanced, even feeling.

Still Not Sure What 1:1 Product is Right for You? MÜV FL Can Help

MÜV FL Patient Care Team
MÜV Patient Care brings genuine care to each and every interaction, be it over the phone, via live chat or email, or even virtual consultation.

Whether you are new to the world of medical marijuana or have been experimenting with different strains and ratios for years, there is always more to learn. The professional staff at MÜV of Florida is here for you. If you have questions before your visit, fill out our online form, and one of our Patient Care Team Representatives will send you a discreet and prompt message in return. We also offer virtual consultations and live chats - our, visit us at a MÜV Florida Dispensary in-person during our store hours for a friendly, face-to-face consultation at your convenience.

We pride ourselves on our mission to provide high-quality cannabis products and accessories that work for a variety of patient needs.

Content Manager for MÜV Florida and Contributor for Zen Leaf Dispensaries. A cannabis connoisseur with a passion for explaining the miraculous possibility of the plant, Swan began her journey with cannabis as a recreational user and quickly realized its positive impact on her depression and severe anxiety. She joined the cannabis industry as Receptionist and MedTender and witnessed first-hand the immense potential of the plant for a wide variety of ailments, deepening her passion for alternative medicine. Swan is dedicated to self-education on the plant and sharing its potential with all. She holds a Journalism degree from the University of Iowa.

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