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10 Best Strains to Try When You Want to Laugh

By MÜV Team October 7, 2025

There’s something special about the kind of laughter that comes from a good smoke session. The right strain can make even the simplest moments feel hilarious, helping you unwind and embrace a lighthearted mood. Whether you’re catching up with friends or just want to turn your day around, certain cannabis varieties are known for sparking smiles, good vibes, and those uncontrollable giggles.

Use this as a guide to find the right option for you, but remember that cannabis is a personal journey and it may take a few different tries to find that perfect strain to make you bust out laughing. Now, let’s break down why some strains make you laugh and which ones are known for spreading joy.

How to Choose a Strain That Promotes Laughter

If your goal is to find a strain that puts you in a cheerful, giggly state, it helps to know what to look for. The most laughter-inducing cannabis types tend to share a few common characteristics:

  • Balanced THC Levels: Moderate to high THC often enhances euphoria and relaxation, setting the stage for a fun, carefree experience.
  • Mood-Boosting Terpenes: Limonene, pinene, and caryophyllene contribute to uplifting, feel-good effects.
  • Sativa or Hybrid Influence: These strains typically promote energy and sociability rather than sedation.
  • Personal Preference: Everyone’s endocannabinoid system reacts differently, so experiment to find what works best for your mood.

10 Strains That Can Turn Up the Laughter

When you’re in the mood to let loose, these strains are known to encourage laughter, positivity, and an overall sense of well-being.

1. Jack Herer

This energizing sativa pays tribute to the legendary cannabis activist it’s named after. Jack Herer delivers a blissful, clear-headed buzz that inspires conversation and laughter. Its piney, citrus aroma and upbeat energy make it a go-to for daytime enjoyment and social events.

2. Durban Poison

A pure sativa known for its sweet and spicy scent, Durban Poison provides a stimulating head high that keeps spirits lifted. It sharpens focus while promoting euphoria, often leaving consumers talkative, creative, and full of laughter.

3. Tangie

Tangie brings a rush of citrus flavor and sunshine to every session. This strain is beloved for its ability to create an energetic, giggly atmosphere. The bright tangerine notes and stimulating high make it perfect for group hangs or creative play.

4. Cereal Milk

With its creamy flavor and balanced hybrid effects, Cereal Milk offers a mood-elevating experience that’s both relaxing and uplifting. It provides an even, happy buzz that makes laughter come easily, especially during lighthearted activities.

5. Lemon Jack

A cross between Lemon Kush and Jack Herer, this sativa-dominant hybrid combines zest and focus. The energetic, euphoric effects make everything feel a little funnier, helping you see the humor in everyday life.

6. GSC (Girl Scout Cookies)

This well-loved hybrid offers a perfect balance between euphoria and relaxation. Its sweet, earthy flavor and deeply satisfying high often bring out bursts of laughter and conversation, making it a favorite for social settings or movie nights.

7. Tropicana Cookies

Tropicana Cookies combines Tangie and Girl Scout Cookies, resulting in a citrus-forward strain that brightens mood and encourages smiles. Its uplifting effects make it ideal for daytime use when you want a fun, carefree high.

8. Wedding Crasher

This hybrid is smooth, sweet, and balanced. Wedding Crasher’s euphoric onset is known to lift spirits and make everything feel a bit more amusing. Its calming physical effects pair perfectly with a joyful, social headspace.

9. Lemon Skunk

Known for its zesty aroma and feel-good vibes, Lemon Skunk offers a steady rise in energy and laughter. It keeps you clear-headed yet carefree, making it perfect for spontaneous hangouts or creative fun.

10. Orange Creamsicle

Sweet, creamy, and citrusy, Orange Creamsicle delivers a mellow, joyful buzz that tends to enhance positivity and humor. It’s a great choice for unwinding with friends or simply lightening the mood after a long day.

Why Cannabis Can Trigger Laughter

Laughter and cannabis often go hand in hand thanks to the way THC interacts with the brain’s endocannabinoid receptors. This interaction enhances dopamine release and boosts connectivity in regions of the brain tied to emotion and social response. In simple terms, cannabis helps people feel more open, relaxed, and connected, which naturally leads to laughter and enjoyment.

Do All Strains Cause Laughter?

Not every strain will spark laughter, and that’s part of the fun of exploring. Strains higher in THC and rich in uplifting terpenes are more likely to create euphoric, giggly experiences, while heavier indicas may lead to calm and introspection instead. If you’re after joy and humor, stick to strains that are known for energy and positivity.

Find Strains That Can Make You Laugh at MÜV

Looking to add more laughter to your day? Visit your local MÜV dispensary in Florida or browse our online menu to find strains that spark happiness, laughter, connection, and good vibes

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MÜV Team

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Welcome to MÜV, where passion for cannabis meets deep-rooted expertise. Our team of authors is a carefully selected group of cannabis experts and pharmacists, each a seasoned professional within the cannabis industry. With diverse backgrounds in pharmacology, journalism, and cannabis, our team of authors provides valuable content designed to help patients make informative cannabis decisions.